NAD+ Nasal Spray — Daily Cellular Energy Support Shipped to Your Door

Powers your mitochondria:Mitochondria are the energy factories inside every cell. They convert the food you eat into ATP — the energy currency your body runs on. NAD+ is essential for this conversion. Without enough NAD+, your mitochondria can't produce energy efficiently, and you feel it as fatigue, brain fog, and reduced physical performance.

Supports DNA repair: Your DNA is constantly being damaged by normal metabolic processes, UV exposure, stress, and environmental toxins. NAD+ activates enzymes called PARPs that repair this damage. When NAD+ levels are low, DNA repair slows down, which accelerates aging and increases cellular dysfunction.

Activates sirtuins: Sirtuins are a family of proteins often called "longevity genes." They regulate cellular health, inflammation, stress resistance, and metabolism. Sirtuins depend entirely on NAD+ to function. When NAD+ declines, sirtuin activity declines — and the protective, anti-aging processes they control slow down.

Supports brain function: Your brain consumes about 20 percent of your body's total energy despite being only 2 percent of your body weight. It's one of the most NAD+-dependent organs. Adequate NAD+ levels support mental clarity, focus, memory, and cognitive performance.



Regulates circadian rhythm: NAD+ helps regulate your body's internal clock, which controls sleep-wake cycles, hormone production, and metabolic timing.

Oral NAD+ supplements (pills, capsules)

When you swallow NAD+, it must pass through your stomach acid and digestive enzymes before reaching your intestines for absorption. Most of the NAD+ molecule is broken down during this process. Some oral supplements use precursors like NMN or NR instead, which your body must then convert into NAD+ — an extra step that adds inefficiency. Bioavailability is limited.a

IV NAD+

therapy

The gold standard for absorption. IV delivery puts NAD+ directly into your bloodstream for 100 percent bioavailability. Reset IV offers NAD+ IV therapy (/treatments/nad-iv-therapy) for clients who want the highest-dose, most direct delivery. However, IV sessions take 45-60 minutes and require a nurse visit.

Nasal spray NAD+

The nasal mucosa is one of the most absorbent surfaces in your body. The thin membrane lining your nasal passages allows molecules to pass directly into your bloodstream, bypassing the digestive system entirely. This gives nasal spray significantly better bioavailability than oral supplements — while being far more convenient than IV therapy. You can self-administer daily at home in seconds.

NAD+ Nasal Spray

Price: $199/month

Best for: Daily NAD+ maintenance, ongoing cellular support, people who want consistent daily supplementation without IV appointments

NAD+ IV Therapy

Price: Starting at 500mg

Best for: High-dose therapeutic sessions, chronic fatigue, cognitive decline, intensive anti-aging protocols, initial NAD+ restoration

Oral NAD+ Supplements (NMN/NR)

Price: $-

Best for: Basic supplementation when other options aren't accessible

Step 1

Virtual Consultation

Schedule a virtual consultation with one of our medical providers. They'll review your health goals, discuss how NAD+ supplementation fits your needs, and confirm the nasal spray is appropriate for you.

Step 2

Shipped to Your Door

Once approved, Reset IV orders your NAD+ Nasal Spray and has it shipped directly to your home within 3 to 5 business days.

Step 3

Self-Administer Daily

Your spray arrives with instructions on how to use it and how to store it properly. Administration takes just seconds — a quick spray in each nostril as directed. The NAD+ passes through your nasal mucosa and into your bloodstream, bypassing your digestive system for better absorption.

Step 4

Monthly Refills, Automatically

Your subscription ensures you never run out. Monthly shipments arrive automatically. Your provider is available for questions about dosing, storage, or how the spray fits into your broader wellness routine.

Administration

Spray into each nostril as directed by your provider. The nasal mucosa absorbs the NAD+ directly into your bloodstream.

Frequency

Daily use as prescribed. Consistent daily administration maintains steady NAD+ levels.

Timing

Many users prefer morning administration for an energy and clarity boost at the start of the day. Your provider can recommend the best timing for your goals.

Storage

Store as directed in the instructions included with your spray. Proper storage ensures potency throughout the month.

Duration

Takes just seconds. No needles, no appointments, no preparation.

Cellular Energy Production

NAD+ is the essential cofactor in the process that converts the food you eat into ATP — the energy molecule every cell uses. When NAD+ levels are adequate, your mitochondria produce energy efficiently and you feel alert, sharp, and physically capable. When NAD+ declines, energy production drops across your entire body — manifesting as fatigue, brain fog, and reduced physical performance.

Healthy Aging and Longevity

NAD+ decline is now recognized as one of the primary hallmarks of biological aging. As NAD+ drops, sirtuin activity decreases, DNA repair slows, mitochondrial function degrades, and inflammation increases. Maintaining NAD+ levels through supplementation supports the molecular processes that keep cells functioning younger longer. This is why NAD+ has become one of the most researched molecules in the longevity science community.

Brain Function and Mental Clarity

Your brain uses about 20 percent of your body's energy while representing only 2 percent of your body weight. It's extremely sensitive to NAD+ levels. Adequate NAD+ supports neuronal energy production, neurotransmitter synthesis, and the cellular repair processes that maintain cognitive function. Many NAD+ users report improved focus, clearer thinking, and better memory.

Muscle Strength and Physical Function

Muscles depend on mitochondrial energy production for strength, endurance, and recovery. Age-related muscle decline (sarcopenia) is closely correlated with declining NAD+ levels. Supporting NAD+ levels may help maintain muscle function and slow age-related physical decline.

Metabolic Support

NAD+ is involved in the metabolic pathways that regulate how your body processes and stores fat, manages blood sugar, and produces energy from food. Supporting these pathways through NAD+ supplementation may complement weight management and metabolic health efforts.

Provider-Supervised

Every subscription begins with a virtual consultation. This isn't an over-the-counter supplement — it's a medically reviewed product.

Shipped to Your Door

No pharmacy visits. Your nasal spray arrives at home within 3 to 5 business days and refills automatically.

$199/month All-In

Consultation fees, service fees, and the nasal spray itself — all included. No hidden costs.

Better Absorption Than Pills

Nasal delivery bypasses your digestive system for significantly better bioavailability than oral NAD+ supplements.

Pair With NAD+ IV Therapy

Use the nasal spray for daily maintenance and book NAD+ IV sessions (/treatments/nad-iv-therapy) for periodic high-dose boosts.

Pharmacy Choice

You can use any pharmacy you prefer, or we'll order from our trusted preferred pharmacy.

Complements Reset IV's Full Lineup

Pair with any of our mobile IV treatments for a comprehensive wellness approach.

NAD+ IV Therapy

The highest-dose NAD+ delivery available. 500mg and 1000mg sessions administered by a nurse at your location. Pair with the nasal spray for daily maintenance between IV sessions.

Peptide Therapy

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Energy Boost IV

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Medical Weight Loss

Semaglutide and Tirzepatide shipped to your door for clinician-supervised weight loss. From $349/month.

Myers' Cocktail 

Broader whole-body wellness with B vitamins, Vitamin C, Magnesium, and Glutathione. $249.