Clinician-Supervised • Self-Injectable • Shipped Nationwide
PT-141 Peptide Therapy — Clinician-Supervised Sexual Enhancement Shipped to Your Door
Sexual desire starts in the brain. When the pathways that trigger arousal aren't firing the way they should — whether from stress, aging, hormonal changes, or other factors — no amount of blood flow support alone can fully restore what's missing. That's where PT-141 is different from anything else on the market.
PT-141, also known as Bremelanotide, is a peptide that works directly in the brain by stimulating the melanocortin receptors in your hypothalamus — the region responsible for sexual desire and arousal. It doesn't just improve blood flow like traditional treatments. It activates the neural pathways that generate actual desire, arousal, and sexual responsiveness. And it works for both men and women.
Reset IV's PT-141 Peptide Therapy is a clinician-supervised, self-injectable subscription shipped directly to your door. After a virtual consultation with a medical provider, your monthly supply arrives at home. You self-inject as needed, about 30 to 60 minutes before sexual activity. Private, convenient, and effective.
Price: $299/month
How PT-141 Works — The Brain-Based Approach to Sexual Enhancement
Most sexual health treatments focus on blood flow. They help blood reach the reproductive organs more effectively, which can improve physical function but doesn't address desire itself. If the mental drive isn't there, improved blood flow only goes so far.
PT-141 takes a fundamentally different approach. It's a melanocortin receptor agonist — meaning it activates specific receptors (melanocortin receptors, specifically MC3R and MC4R) in the hypothalamus, the part of your brain that controls sexual desire, arousal, and hormonal signals. When these receptors are activated, they trigger the neural cascade that produces genuine sexual desire, increased arousal, and heightened responsiveness.
This brain-based mechanism is what makes PT-141 unique:
It addresses desire, not just function: Traditional treatments help with the physical mechanics of arousal. PT-141 helps generate the desire that drives those mechanics in the first place.
It works for both men and women: Because it operates through the brain's arousal pathways rather than a gender-specific blood flow mechanism, PT-141 supports sexual enhancement for both men and women.
It complements other approaches: PT-141 can work alongside blood-flow-focused treatments for a more comprehensive approach to sexual wellness.
After subcutaneous injection, PT-141 typically takes 30 to 60 minutes to take effect. The effects can last for several hours, giving you a natural window of enhanced desire and responsiveness.
Benefits of PT-141 Peptide Therapy
Enhanced sexual desire and libido
PT-141 activates the brain's arousal pathways to help restore and heighten sexual desire — the mental and emotional drive that initiates intimacy.
Improved sexual arousal and performance
By stimulating the neural pathways that control arousal, PT-141 supports stronger, more responsive physical arousal in both men and women.
Boosted erectile function
For men experiencing erectile dysfunction, PT-141 provides a brain-based approach that can complement or serve as an alternative to traditional blood-flow treatments.
Stronger orgasmic response
Heightened desire and arousal can contribute to more intense and satisfying orgasmic experiences.
Enhanced emotional connection and intimacy
When desire and arousal are restored, many couples report feeling more connected and emotionally present during intimacy.
Works for both men and women
PT-141 is one of the few sexual enhancement options designed to be effective for both genders.
PT-141 vs. Traditional Sexual Health Treatments
Reset IV offers NAD+ IV therapy in 500mg and 1000mg doses, delivered via mobile service directly to your location. Each infusion includes a saline base for hydration and can be customized with add-on vitamins and supplements.
Traditional ED Medications (Blood Flow Approach)
Price: $-
How they work:
Increase blood flow to reproductive organs by relaxing blood vessel walls.
What they address:
Physical mechanics of arousal — primarily erectile function in men.
What they don't address:
Desire, libido, or mental arousal. If the desire isn't there, improved blood flow may not be enough.
Gender:
Designed primarily for men. Limited effectiveness for women.
PT-141 (Brain-Based Approach)
Price: $-
How it works:
Activates melanocortin receptors in the hypothalamus to stimulate sexual desire and arousal at the brain level.
What it addresses:
Desire, libido, arousal, responsiveness, and sexual satisfaction.
Unique advantage:
Targets the source of desire rather than just the physical mechanics. Can restore the mental and emotional drive for intimacy.
Gender:
Effective for both men and women.
Reset IV Sexual Health Support IV (Amino Acid Approach)
Price: $-
How it works:
Delivers L-Arginine, Citrulline, and other amino acids that support nitric oxide production for improved blood flow.
What it addresses:
Circulation, blood flow to reproductive organs, energy, and stamina.
Best used:
For general sexual wellness support through natural blood flow enhancement. $309 per session.
Many clients combine PT-141 with the Sexual Health Support IV for a comprehensive approach — PT-141 for brain-based desire and the IV for blood-flow support. Consult your medical provider about what combination is right for you.
PT-141 for Men and Women
For Men
PT-141 is particularly valuable for men experiencing erectile dysfunction or reduced libido. Many men have tried traditional ED treatments that improve blood flow but still find that desire itself is diminished — especially with age, stress, or fatigue. PT-141 addresses this by working at the brain level, stimulating the desire pathways that blood-flow medications don't reach. It can be used as a standalone treatment or alongside other approaches for comprehensive support.
For Women
Low sexual desire is one of the most common sexual health concerns among women, yet there are very few effective treatments available. PT-141 is one of the few options clinically studied for female sexual dysfunction. By activating the brain's arousal centers, it can help restore the desire, responsiveness, and satisfaction that stress, hormonal changes, and aging may have diminished. Many women report renewed interest in intimacy and improved overall sexual experience.
For Couples
Both partners can use PT-141. For couples where desire has declined on one or both sides, PT-141 can help reignite the spark and improve the intimate experience for everyone involved. Our medical provider can discuss options during your virtual consultation.
How It Works
Step 1
Virtual Consultation
Schedule an online consultation with one of our medical providers. They'll review your health history, discuss your sexual health goals, and determine if PT-141 is appropriate for you.
Step 2
PT-141 Shipped to Your Door
Once approved, your PT-141 injectable kit is shipped directly to your home. Most orders arrive within one week.
Step 3
Self-Administer as Needed
PT-141 is a subcutaneous injection — a small needle injected just under the skin, typically in the thigh, abdomen, or upper arm. Administer approximately 30 to 60 minutes before sexual activity. Your kit includes detailed instructions. Effects typically last several hours.
Step 4
Monthly Refills
Your subscription ensures a continuous supply. Monthly shipments arrive automatically so you're never without your medication. Your medical provider is available for dosage questions and adjustments.
How to Use PT-141
Injection type
Subcutaneous (under the skin) — not intramuscular or intravenous. A small, thin needle.
Injection sites
Thigh, abdomen (at least 2 inches from navel), or upper arm. Rotate sites between uses.
Timing
Inject approximately 30 to 60 minutes before anticipated sexual activity.
Onset
Effects typically begin within 30 to 60 minutes.
Duration
Effects can last for several hours. Duration varies by individual.
Frequency
Use as needed. Your medical provider will advise on appropriate frequency.
Storage
Keep PT-141 injections refrigerated to maintain effectiveness.
Technique
Pinch the skin at your injection site, insert the needle fully, inject, hold briefly, then remove. Detailed instructions are included with your kit.
What to Expect — Side Effects and Safety
Common Side Effects
PT-141 may cause mild side effects, particularly during the first few uses as your body adjusts:
- Nausea: The most commonly reported side effect. Usually mild and temporary. Eating a light meal before injection can help.
- Headache: Some users experience a mild headache that resolves within a few hours.
- Flushing: Temporary warmth or redness, particularly in the face. A normal response to the peptide's activity.
- Slight blood pressure increase: A temporary, minor increase that typically resolves quickly. Inform your provider if you have existing blood pressure concerns.
These side effects typically diminish with continued use as your body becomes accustomed to the peptide. If any side effects persist or cause concern, contact your medical provider for guidance.
Safety Considerations
- Consult your provider about interactions: Discuss all current medications with your provider before starting PT-141, particularly blood pressure medications or heart medications.
- Not for use during pregnancy: PT-141 should not be used during pregnancy or while breastfeeding.
- Medical supervision required: A virtual consultation is required before any PT-141 prescription is issued. This is a medically supervised treatment, not an over-the-counter supplement.
Who Is PT-141 For?
Men experiencing erectile dysfunction: Especially those who want a brain-based approach or who haven't found complete satisfaction with blood-flow-only treatments.
Women experiencing low sexual desire: One of the few clinically studied options for female sexual dysfunction. Addresses desire at the neurological level.
People who've tried other treatments without full results: If traditional approaches have improved physical function but haven't restored desire, PT-141 targets what those treatments miss.
Couples looking to enhance intimacy: Both partners can use PT-141 to align desire and improve shared experiences.
People dealing with stress-related sexual issues: Chronic stress suppresses the brain's arousal pathways. PT-141 helps reactivate them.
People experiencing age-related desire decline: Desire naturally changes with age. PT-141 supports the neural pathways that aging may have slowed.
Anyone seeking a convenient, at-home solution:
Self-injectable, shipped to your door, no clinic visits after your initial consultation.
Why Choose Reset IV for PT-141
Clinician-Supervised
Every prescription requires a virtual consultation with a medical provider. This is supervised medicine, not a supplement.
Shipped to Your Door
Your PT-141 arrives at home. No pharmacy lines, no clinic visits after your consultation.
Private and Discreet
Discreet packaging, private consultation, confidential treatment. No awkward conversations in public.
$299/month
Straightforward monthly pricing. No hidden fees.
For Men and Women
PT-141 is one of the few sexual enhancement treatments effective for both genders.
Brain-Based, Not Just Blood Flow
Addresses desire and arousal at the source — the brain — for a more complete approach to sexual wellness.
Complements Other Reset IV Treatments
Pair with the Sexual Health Support IV ($309) for combined brain-based and blood-flow support.
FAQ's
Frequently Asked Questions
What is PT-141?
PT-141, also known as Bremelanotide, is a peptide that activates melanocortin receptors in the hypothalamus — the part of your brain responsible for sexual desire and arousal. Unlike blood-flow-based treatments, PT-141 works at the neurological level to enhance libido, arousal, and sexual responsiveness. It's effective for both men and women. $299/month, shipped to your door.
How does PT-141 work?
PT-141 stimulates MC3R and MC4R melanocortin receptors in the brain, triggering the neural cascade that produces sexual desire and arousal. This is a fundamentally different mechanism than blood-flow treatments — it targets the source of desire rather than just the physical mechanics.
Does PT-141 work for women?
Yes. PT-141 is one of the few sexual enhancement treatments clinically studied for female sexual dysfunction. By activating the brain's arousal pathways, it can help restore desire, responsiveness, and satisfaction in women experiencing low libido.
How do I use PT-141?
PT-141 is a subcutaneous injection administered with a small needle in your thigh, abdomen, or upper arm. Inject approximately 30 to 60 minutes before anticipated sexual activity. Effects typically last several hours. Your kit includes detailed instructions.
How quickly does it work?
PT-141 typically takes 30 to 60 minutes to take effect after injection. Effects can last for several hours, varying by individual.
What are the side effects?
Common side effects include nausea, headache, flushing, and a slight temporary increase in blood pressure. These are usually mild and diminish with continued use. Contact your provider if side effects persist.
How much does PT-141 cost?
$299/month. This includes your virtual consultation and monthly PT-141 supply shipped to your door.
How is this different from traditional ED treatments?
Traditional ED treatments work by increasing blood flow to reproductive organs. PT-141 works in the brain by activating the desire and arousal pathways that generate sexual interest in the first place. It addresses desire, not just function — and works for both men and women.
Can I use PT-141 with other medications?
Consult your medical provider before combining PT-141 with other medications, especially those affecting blood pressure or heart function. Your provider will review your full medication history during the virtual consultation.
How should I store PT-141?
Keep PT-141 injections refrigerated to maintain effectiveness. Detailed storage instructions are included with your kit.
How long until my order arrives?
Most orders arrive within one week after your virtual consultation and approval. Monthly refills ship automatically.
How do I get started?
Visit resetiv.com or call/text 1-844-387-4870. You'll schedule a virtual consultation with a medical provider. Once approved, your PT-141 ships directly to your door.
Desire Starts in the Brain. Reactivate It.
PT-141 is the peptide that works where other sexual health treatments can't — in the brain's arousal and desire pathways. For men, for women, for couples. Clinician-supervised, self-injectable, shipped to your door. $299/month. Private, discreet, and effective.
Medical Disclaimer
Medical Disclaimer:
The information on this page is for educational purposes only and is not intended as medical advice. A virtual consultation with a medical provider is required before any prescription is issued. PT-141 is a prescription peptide that requires medical supervision. These services have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Do not use PT-141 if you are pregnant or breastfeeding. Always consult your physician before beginning any treatment or therapy program, especially if you are taking other medications. Any designations or references to therapies are for marketing purposes only and do not represent actual products. If you are experiencing a medical emergency, call 911.
